Preliminary Workshop Program

Sunday, June 17  
   
18:00 - 21:00 Registration
   
19:00 - 22:00 Welcome banquet
   
   
Monday, June 18  
   
08:45 - 09:00 Opening
  Frank Jülicher (Managing Director MPIPKS)
   
  Session: NETWORKS
  Chair: Rob Russell
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:50 Daniel Segré (Boston University)
  Evolutionary constraints in metabolic and genetic networks
   
09:50 - 10:15 Marc-Thorsten Hütt (Jacobs University Bremen)
  Network control in gene expression profiles
   
10:15 - 10:40 Johannes Berg (University Cologne)
  Statistical analysis of networks: Clusters, motifs, cross-species correlations
   
10:40 - 11:10 Coffee break
   
11:10 - 11:55 Michael Schroeder (Technical University Dresden)
  From domain-domain to protein-protein interactions and back
   
11:55 - 12:40 Pietro Liò (University of Cambridge)
  Inferring transcriptional noise using protein dipole statistics
   
12:40 - 12:55 Concluding discussion
   
12:55 - 14:10 Lunch break
   
  Session: TRANSCRIPTIONAL REGULATION
  Chair: Leonid Mirny
   
14:10 - 14:15 Chair: Introduction to the session
   
14:15 - 15:00 Michael Lässig (University of Cologne)
  Transcriptional regulation: From biophysics to evolution
   
15:00 - 15:45 Stefan Bornholdt (University of Bremen)
  Physics of genetic networks: Reliable control of the living cell in the presence of biochemical stochasticity
   
15:45 - 16:00 Concluding discussion
   
16:00 - 16:30 Coffee break
   
16:30 - 17:30 PCFBIM07 Colloquium
  Eytan Domany (Weizman Institute)
  Predicting outcome in cancer: Hope, hype, physics and ... biology
   
19:00 - 20:30 Dinner break
   
20:30 - ... Discussion session
   
   
Tuesday June 19  
   
  Session: PROTEIN STRUCTURE AND FUNCTION
  Chair: Michael Sternberg
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:50 Angel Ortíz (Universidad Autonoma de Madrid)
  Merging physics and evolution in protein structure prediction by homology modelling
   
09:50 - 10:15 Julián Echave (CONICET Argentina)
  A model of protein structural divergence to explain why structures evolve along the slowest collective vibrational normal modes
   
10:15 - 10:40 Ugo Bastolla (Universidad Autonoma de Madrid)
  Selective and mutational constraints in the evolution of protein folding thermodynamics and kinetics
   
10:40 - 11:10 Coffee break
   
11:10 - 11:55 Christine Orengo (University College London)
  Comparative and structural genomics to explore the evolution of protein function
   
11:55 - 12:40 Rob Russell (EMBL Heidelberg)
  Predicting aspects of binding affinity from proteomics or structure data
   
12:40 - 12:55 Concluding discussion
   
12:55 - 14:10 Lunch break
   
  Session: PROTEIN STRUCTURE, FOLDING, AND COMPLEXES
  Chair: Christine Orengo
   
14:10 - 14:15 Chair: Introduction to the session
   
14:15 - 15:00 Hunter Fraser (Broad Institute)
  Protein complexes and human disease
   
15:00 - 15:45 Liisa Holm (University of Helsinki)
  Sequence alignment detects as many remote homologues as sequence-structure threading
   
15:45 - 16:15 Coffee break
   
16:15 - 17:00 Michael Sternberg (Imperial College)
  The identification of similarities between biological networks
   
17:00 - 17:45 Amnon Horovitz (Weizman Institute)
  Conformational changes in chaperonins: Function and mechanism
   
17:45 - 18:00 Concluding discussion
   
19:00 - 20:30 Dinner break
   
20:30 - ... Poster session
   
   
Wednesday June 20  
   
  Session: BIOINFORMATICS
  Chair: Liisa Holm
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:50 Pierre Baldi (University of California, Irvine)
  Charting chemical space with computers: Challenges and opportunities for AI and machine learning
   
09:50 - 10:35 Sarah Teichmann (MRC Laboratory of Molecular Biology)
  Evolution of protein-protein interactions in complexes and networks
   
10:35 - 11:05 Coffee break
   
11:05 - 11:50 Jens Meiler (Vanderbilt University)
  Computational structural bio-chemistry: Methods and application
   
11:50 - 12:05 Concluding discussion
   
12:05 - 14:00 Lunch
   
14:00 Excursion
   
19:30 Conference dinner at the restaurant ``Kurhaus Kleinschachwitz''
   
   
Thursday June 21  
   
  Session: PROTEIN STRUCTURE SPACE
  Chair: Pierre Baldi
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:50 Sung-Hou Kim (University of California, Berkeley)
  Mapping of the protein structure universe: Evolution of structure and function of proteins
   
09:50 - 10:35 Dmitrij Frishman (Technical University Munich)
  Structural genomics of membrane proteins: Fold space, target selection, and structure prediction
   
10:35 - 11:05 Coffee break
   
11:05 - 11:50 Andrew Lee (University of North Carolina, Chapel Hill)
  Using intramolecular dynamics by NMR for understanding long-range effects in proteins
   
11:50 - 12:35 Shmuel Pietrokovski (Weizman Institute)
  Relations between protein sequence conservation, structure, and function
   
12:35 - 12:50 Concluding discussion
   
12:50 - 14:10 Lunch break
   
  Session: DNA AND RNA
  Chair: Dmitrij Frishman
   
14:10 - 14:15 Chair: Introduction to the session
   
14:15 - 15:00 Ralf Bundschuh (The Ohio State University)
  Quantitative models of RNA single molecule experiments
   
15:00 - 15:25 Enrico Carlon (Katholieke Universiteit Leuven)
  Hybridization thermodynamics in DNA microarrays
   
15:25 - 15:55 Coffee break
   
15:55 - 16:40 Leonid Mirny (Massachusetts Institute of Technology)
  How genome structure is influenced by the biophysics of gene regulation
   
16:40 - 17:05 Christina Kiel (Centre Regulacio Genomica)
  Prediction of protein-protein interactions based on structural information
   
17:05 - 17:30 Helge Roider (MPI for Molecular Genetics)
  Predicting transcription factor affinities to DNA from a biophysical model
   
17:30 - 17:45 Concluding discussion
   
19:00 - 20:30 Dinner break
   
20:30 - ... Poster session
   
   
Friday June 22  
   
  Session: GENETICS AND EPIGENETICS
  Chair: Sung-Hou Kim
   
09:00 - 09:05 Chair: Introduction to the session
   
09:05 - 09:50 Christos Ouzounis (EMBL Cambridge)
  Quantifying vertical and horizontal gene flow across species and time
   
09:50 - 10:35 Edo Kussell (New York University)
  Population dynamics of phenotype-switching bacteria
   
10:35 - 10:50 Concluding discussion
   
10:50 - 11:20 Coffee break
   
  Session: SYSTEMS BIOLOGY
  Chair: Sung-Hou Kim
   
11:20 - 11:25 Chair: Introduction to the session
   
11:25 - 12:10 Hans Westerhoff (Universiteit Amsterdam)
  Physicochemical foundations of systems biology: From self-organization to vertical genomics
   
12:10 - 12:25 Concluding discussion
   
12:25 - 12:40 Closing
   
12:40 Lunch/Departure


Last updated: June 15, 2007